Athletes who take human growth hormone may not be getting the boost they expected.

While growth hormone adds some muscle, it doesn’t appear to improve strength or exercise capacity, according to a review of studies that tested the hormone in mostly athletic young men.

“It doesn’t look like it helps and there’s a hint of evidence it may worsen athletic performance,” said Dr. Hau Liu, of Santa Clara Valley Medical Center in San Jose, Calif., who was lead author of the review.

Growth hormone, or HGH, is among the performance enhancers baseball stars Roger Clemens and Andy Pettitte were accused of taking in the blockbuster Mitchell Report. Clemens denies using the hormone, while Pettitte admits using it.

But the new research has some limitations and sheds no light on long-term use of HGH. The scientists note their analysis included few studies that measured performance. The tests also probably don’t reflect the dose and frequency practiced by athletes illegally using the hormone. Experiments like that aren’t likely to be conducted.

“It’s dangerous, unethical and it’s never going to be done,” said Dr. Gary I. Wadler, a member of the World Anti-Doping Agency and a spokesman for the American College of Sports Medicine.
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